Posts Tagged: aspirin

Stroke Caused by Atherosclerosis of the Major Intracranial Arteries

Stroke Caused by Atherosclerosis of the Major Intracranial Arteries

Chirantan Banerjee, Marc I. Chimowitz

Histological cross-section of intracranial atherosclerosis in basilar artery. Image courtesy Dr Tanya Turan. Red arrow—fibrous tissue, blue arrow—vessel wall, and green arrow—lipid [Powerpoint File]

Historical Lessons in Translational Medicine: Cyclooxygenase Inhibition and P2Y12 Antagonism

 Historical Lessons in Translational Medicine: Cyclooxygenase Inhibition and P2Y12 Antagonism

Desmond J. Fitzgerald, Garret A. FitzGerald

Schematic of the absorption and metabolism of clopidogrel. Oral clopidogrel is predominantly metabolized by liver carboxylesterases to inactive metabolites. Lesser amounts are metabolized by liver cytochrome P450 enzymes, including CYP2C19, which forms the active metabolite. {Powerpoint File]