Human Induced Pluripotent Stem Cell–Derived Cardiomyocytes: Insights Into Molecular, Cellular, and Functional Phenotypes

Human Induced Pluripotent Stem Cell–Derived Cardiomyocytes: Insights Into Molecular, Cellular, and Functional Phenotypes

Ioannis Karakikes, Mohamed Ameen, Vittavat Termglinchan, Joseph C. Wu

Current applications of patient-specific induced pluripotent stem cell–derived cardiomyocyte (iPSC-CM) technology. iPSC-CMs have been used for disease modeling of inherited cardiomyopathies and channelopathies, regenerative therapies, drug discovery, and cardiotoxicity testing, as well as for studying metabolic abnormalities and cardiac development. [Powerpoint File]

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